Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
نویسندگان
چکیده
منابع مشابه
Interleukin-17-dependent autoimmunity to collagen type V in atherosclerosis.
RATIONALE Considerable evidence shows atherosclerosis to be a chronic inflammatory disease in which immunity to self-antigens contributes to disease progression. We recently identified the collagen type V [col(V)] α1(V) chain as a key autoantigen driving the Th17-dependent cellular immunity underlying another chronic inflammatory disease, obliterative bronchiolitis. Because specific induction o...
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ژورنال
عنوان ژورنال: Immunity
سال: 2008
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2008.07.018